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Vacuum freeze-drying technology is widely used in biological engineering, pharmaceutical industry, food industry, material science and deep processing of agricultural and sideline products. Drug freeze-drying includes two parts: western medicine and traditional Chinese medicine. Freeze-drying of western medicine has been developed in China. Many larger pharmaceutical factories have freeze-drying equipment. In terms of injection, freeze-drying technology is widely used, which improves the quality and storage period of drugs and brings benefits to both doctors and patients. 

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But at present the variety of freeze-drying medicine is not much, the product price is high, the drying technology is not advanced. In the aspect of traditional Chinese medicine, it is still limited to the freeze-drying of ginseng, deer antler, Chinese yam, cordyceps sinensis and a few other traditional Chinese medicinal materials at present. A large number of Chinese patent medicines have not been freeze-dried, which is a big gap with foreign countries.

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A few years ago, Japan launched the "western preparation of Chinese medicine", which changed the method of decoction of traditional Chinese medicine, solved the tradition that traditional Chinese medicine could not be made into injection or tablet, and also solved the problem that traditional Chinese medicine could not treat acute diseases. Therefore, the research on freeze-drying technology and products of traditional Chinese medicine in China has great potential. In the field of biotechnology products, freeze-drying technology is mainly used in the production of serum, plasma, vaccines, enzymes, antibiotics, hormones and other drugs. Biochemical test drugs, immunological and bacteriological test drugs; Long-term preservation of blood, bacteria, arteries, bones, skin, cornea, nerve tissue and various organs.

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Batch freeze-drying equipment is suitable for many varieties of small batch production, especially in the field of food suitable for seasonal strong food production. Single machine operation, if one equipment failure, will not affect the normal operation of other equipment. The intermittent freeze-drying equipment is convenient to control the heating temperature and vacuum degree in different stages of material drying. The equipment is easy to manufacture and maintain. However, due to the loading, unloading, starting and other operations take more time, so the equipment utilization rate is low, production efficiency is not high.

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In recent years, continuous vacuum freeze-drying equipment has been explored and used at home and abroad. The continuous equipment is suitable for the production of single variety, large output and abundant raw materials, especially for the production of slurry and granular products. Continuous equipment is easy to realize automatic control, simplifies manual operation and management, its main disadvantage is high cost.

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